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Toned Protein Boost

Supercharge your routine, enhance your diet and curb your cravings with Intrametica® Toned Protein Boost. This smoothie enhancer will transform your skin & metabolism from within, with a blend of sprouted, bio-fermented organic plant protein boosted with marine bioactive collagen peptides. We’ve also included a clinically proven proprietary blend of Italian Moro Oranges, Carob Seed Antioxidants and Fibre, Sea Minerals and Coconut Water Electrolytes for ultimate skin nourishment and radiance.

Ingredients

  • Organic Sprouted Fermented Brown Rice Protein
  • Organic Sprouted Fermented Pea Protein
  • Fish Collagen (Bioactive peptides)
  • Moro Red Orange (Citrus sinesis (L.) Osbeck)
  • Carob (Ceratonia siliqua) seed powder
  • Red Marine Algae (Lithothamnion sp)
  • Peruvian Raw Sacha Inchii Protein*
  • Pumpkin Seed Protein*
  • Sunflower Seed Protein*
  • Flaxseed meal*
  • Coconut Water*
  • Mesquite*

The Evidence

Organic Sprouted Fermented Brown Rice Protein

Cut to the chase:

It will help you lose body fat.

Want the evidence?

Brown rice is an excellent source of protein, containing 37% of the total protein as essential amino acids and 18% as BCAA 1,2. Rice protein has been shown to modify triglyceride metabolism, leading to an improvement of body weight and adiposity. These effects are attributed to the upregulation of lipolysis and downregulation of lipogenesis, and the lower digestibility of rice protein may be the main modulator, responsible for the lipid-lowering action 3. An animal study demonstrates the endogenous antioxidant potential of rice proteins via mechanism through which, Nrf2 activation plays an essential role in inducing Phase II antioxidants/detoxification enzymes and preventing ROS generation, initiated by the supplementation of rice proteins 4.

Cut to the chase:

You will not feel as hungry.

Want the evidence?

Pea protein is effective in lowering short-term food intake after a preload meal containing 20g of protein 30 minutes later. Studies also establish that there is a higher feeling of satiety after the pea protein 5. Pea protein has been shown to suppress appetite compared to whey protein in overweight subjects. An in-vivo study shows that pea protein has a fast intestinal bioavailability and was effective in triggering gastrointestinal satiety signals CCK, GLP-1 and PYY. Pea protein stimulated these anorexigenic gut peptide release and promoted satiety signaling 6. This study also established that the total integrated ghrelin response over 3 hours was the same for pea protein as for whey protein, with pea protein stimulating a lower insulin response post meal. High protein diets are more satiating and frequently improves weight loss and body composition due to the release of CCK, GLP-1 and PYY anorexigenic gut hormones. Diets that contain a high-protein preload are shown to induce a lower intake of food compared to high carbohydrate foods 7.

Cut to the chase:

You’ll have less wrinkles and firmer skin.

Want the evidence?

Supplemental collagen stimulates the skin to produce more collagen which causes changes in the skin (Dermis layer) providing a more plump appearance. This delays the signs of skin aging – from the inside out as skin function and healthy appearance depend on, a sufficient supply of essential nutrients and therefore it is possible to modulate or delay skin aging and improve skin integrity through supplementation. Studies showed a significant reduction in eye wrinkle volume after 8 weeks of taking 2.5mg of bioactive collagen peptides. The maximum reduction in eye wrinkle volume of 50% was achieved after 8 the weeks. Preclinical studies have shown that collagen peptides have stimulatory effects on type 1 collagen in fibroblasts – this increases the skin’s rejuvenation properties – reducing the aging appearance of skin. Increase in Fibrillin and elastin content after 8 week supplementation with bioactive collagen peptides was also demonstrated. Bioactive collagen peptide studies showed that women noticed a reduction in the appearance of cellulite and improved skin tone after 6-month supplementation of 2.5g daily. Skin elasticity, skin moisture, transepidermal water loss and skin roughness were measured for 8 weeks after supplementation of 2.5g or 5g of Collagen peptides. Results were seen after 4 weeks of treatment, with women having 30% increase in skin elasticity with more significant results seen in women over 50 years old 8,9,10,11.

Collagen peptides are a versatile source of protein and an important element of healthy nutrition. Their nutritional and physiological properties promote the health of bones and joints, and contribute to beautiful skin 12.

Collagen consists of three polypeptide chains. These α-chains are wrapped around each other to form triple-helical macromolecules: a unique structure, size and amino acid sequence. In collagenous sequences, glycine (Gly) is present as every third residue. This enables the formation of the three chains into a triple-helical structure. Thus, the common feature for all collagens is a sequence that can be expressed as (Gly-X-Y)*n, where X and Y are frequently represented by proline (Pro) and hydroxyproline (Hyp), respectively. This sequence is necessary for the collagen to assemble the fibrils that subsequently form fibers, providing unmatched structural integrity for the extracellular matrix of conjunctive tissues 13,14,15.

The raw material for collagen peptides – as for gelatin – is collagen protein. Collagen peptides, however, are relatively small molecules with a molecular weight of less than 10,000 g/mol. The peptides comprise at least two and at most 100 amino acids. They are characterized by excellent cold-water solubility and even in highly concentrated solutions, they do not form a gel.

Marine bioactive proteins and peptides, depending on their structures and amino acid sequences, exhibit a wide range of biological activities including antioxidant, antimicrobial, anticancer, immunomodulatory, antihypertensive, anticoagulant, and anti-diabetic effects 16,17,18,19,20,21,22.

Cut to the chase:

This stuff helps you lose weight

Want the evidence?

Moro red orange is a potent source of flavonoids that affect the metabolism of fat cells, counteracting fat accumulation and reducing weight gain. Toned Protein Boost contains the same amount of Moro red orange which was trialed over 12 weeks causing a significant reduction is weight, BMI, waist and hip circumference in comparison with the group that didn’t have the Moro orange 23.

A diet high in anthocyanins have been shown to directly target the adipocytes (fat cells) to reduce the accumulation of fat and body weight. Anthocyanins have been reported to behave directly as antioxidants, thereby providing protection from DNA, protein and lipid damage. At a cellular level, anthocyanin’s produce different effects: they inhibit tumorigenesis by blocking activation of a mitogen-activated protein kinase pathway,18 reduce estrogenic activity, induce cytokine production and decrease capillary permeability,19 whereas when administered to adipocytes, anthocyanins exert a protective role against H2O2 or tumor necrosis factor-a-induced insulin resistance 24,25,26.

A randomised controlled trial showed a reduction in body weight gain, BMI and waist and hip circumference in overweight subjects were all reduced when taking Moro orange concentrate. This study shows that anthocyanins have a significant potency of anti-obesity and ameliorate adipocyte function in in vitro and in vivo systems and also that, they have important implications for preventing metabolic syndrome 27.

Cut to the chase:

You’ll have more energy

Want the evidence?

Carob is a polyphenol rich source of insoluble fibre (cellulose, hemicellulose, lignin and insoluble polyphenols) that has been shown to influence hunger, satiety and reduce overall energy intake.

Studies have examined that Carob consumption increases satiety, lowers energy intake at meal time, and decreased post meal glycemic response possibly due to its low GI value indicating that it can be used in body weight control and blood sugar regulation, helping to keep you fuller for longer and reducing energy slumps. Dietary fibre intake has positive effects on gut hormone production of Ghrelin as this regulates satiety and energy intake.

In humans, consumption of carob fiber was shown to have a high antioxidant capacity and to lower serum cholesterol and serum triglycerides additionally, polyphenols may increase fat oxidation and energy expenditure in humans. Therefore, carob fiber may exert beneficial effects on postprandial lipid metabolism and substrate utilization potentially related to the secretion of gut hormones 28,29,30.

Cut to the chase:

Your hair, skin and nails will be even more gorgeous

Want the evidence?

Natural Multi-Mineral Marine Complex from sustainably sourced seaweed grown in the Fjords of Iceland contains over 72 trace minerals and provides a source bio-active calcium and magnesium. Our proprietary material is clinically trialled for bone, joint and digestive health 31,32.

Trace minerals provide the skin, hair and nails with the required substrate to function at an optimal levels, this includes antioxidant activity, anti-inflammatory, photoprotection and collagen formation.

Zinc is an essential trace element that pays an important role in skin, nail and hair health. Zinc is a cofactor required for cell membrane repair, cell proliferation and growth and wound healing. Zinc is also required as a cofactor for protein assimilation for DNA repair, metabolic processing and antioxidant defences and therefore a zinc deficiency can affect the quality and function of hair, skin and nails 33.

Nutritional supplementation of marine based products, plant extracts and micronutrients positively affect the skins appearance, by reducing oxidative stress and inflammation and after 24 weeks of supplementation improved the appearance of the skin. Owing to Lithothamnion’s ability to reduce nuclear factor kappa B (NF-κB – a central regulator of the immune response), and cyclo-oxygenase-2 gene expression, this mineral was studied in animals later showing promising outcomes for the treatment of ulcerative dermatitis. The dysregulation of NF-κB contributes to the pathogenesis of many autoimmune and inflammatory diseases 34,35.

Alterations in diet and nutritional deficiency’s and deprivation can play a role in the way the skin is functions and can lead to premature aging, skin dehydration, roughness and barrier function 36,37.

Cut to the chase:

You’ll be better hydrated

Want the evidence?

Coconut water has advantages as a natural source of electrolytes and carbohydrates whilst being low in fat and sugar and is effective in providing rehydration. A small study of men (n=8) showed that coconut water was effective as a rehydrating fluid after strenuous physical exercise 38,39.

Cut to the chase:

This is your sweet daily dose of fibre

Want the evidence?

Mesquite bean (Prosopis juliflora) is a legume and is considered to be a weed “of national significance” in Australia, because of its invasiveness, potential for spread, and economic and environmental impacts. There are over fourty species of Prosopis world-wide, which are all collectively known as mesquite 40. The Native Americans had many different uses and methods of storage for the mesquite pods. The men would take mesquite cakes (made with mesquite powder and water) hunting with them, as their main source of carbohydrate to complement the protein (from small mammals, birds and fish). Other uses of the pods included making beverages, syrups and animal feed.

Adding mesquite to your diet can give you long-lasting energy and satiety. Mesquite is known for its sweet flavor, with undertones of nuttiness and caramel, but it has a remarkably low glycemic index (GI) of just 25. This low GI helps to maintain stable blood sugar levels.

Part of the reason for mesquite’s low GI is its high mineral content. Mesquite powder boasts an impressive nutritional profile, it contains.

  • Calcium
  • Magnesium
  • Potassium
  • Iron
  • Zinc
  • Lysine

Mesquite is also a concentrated source of fiber – meaning it takes your body longer to break down and digest it, which also helps to keep blood sugar levels stable. Mesquite contains high levels of protein – between 11% and 17% 41.

Cut to the chase:

Your skin will be clear

Want the evidence?

Sacha inchi is a perennial plant that is native to South America and may be called by a number of names, including Inca Peanut and Mountain Peanut. The scientific name of this plant is Plukenetia volubilis. The fruit of this plant is small and star-shaped, containing 4-7 pods. It becomes green upon ripening, but they are commonly allowed to dry, so the inedible pulp inside the fruit can dry, leaving the seeds easy to separate and consume. There is one seed in each of the pods of the fruit, and the seeds are quite similar to almonds, both in taste and accessibility within the seed pod. You cannot eat the seeds raw, but after roasting these seeds, they can be a delicious and an incredibly healthy snack, thanks to the high concentration of nutrients found inside. In fact, sacha inchii seeds have been widely called the newest “superfood” in certain natural healing circles. The oil derived from these seeds is also highly sought after for its concentration of antioxidants and active organic compounds.

With a high level of omega-3 and omega-6 fatty acids, as well as various antioxidants, these tasty seeds can be an excellent addition to your skincare regimen. They are able to help in improving the appearance of the skin, while also reducing wrinkles, age spots, and blemishes. In addition, they have soothing anti-inflammatory properties that help prevent psoriasis and eczema 42,43,44,45.

Cut to the chase:

You can keep your blood sugar levels low

Want the evidence?

Flaxseeds contain about 55 % alpha-linolenic acid (ALA), 28–30 % protein and 35 % fiber and phytoestrogens (lignans). Flaxseed lignans behaviour depends on biological levels of estrogen hormone. At normal levels of estrogen, lignans exhibit antagonistic activity, but in postmenopausal phase when estrogen level is low, flaxseed lignans acts as weak safe estrogen 46,47. Dietary fiber of flaxseed reaches the large intestine and is fermented by colonic microflora with production of short chain fatty acids (SCFA) making flaxseeds beneficial for gut health 48. Flaxseed fiber plays an important role in lowering the blood glucose levels. Studies demonstrated that insoluble fiber slows down the release of sugar in the blood and thus help in reducing blood glucose levels to great extent 49,50,51

Pumpkin Seed and Sunflower Seed Proteins have been included in Toned Protein Boost to provide plant based essential fatty acids, fibre and nutritionally dense protein sources to help balance blood sugar profiles by helping you feel fuller, for longer.

Dosage

Adults – Take two rounded tablespoons (20 grams) a day with 200mL of water, juice or sprinkle over food or add to your favourite smoothie blend or as professionally prescribed by your healthcare practitioner.

Children – Not suitable for children under 15 years unless specifically prescribed by a qualified healthcare practitioner.

Cautions

Not recommended for use during pregnancy and breast-feeding.

Consult your healthcare professional before use if you have had renal calculi (kidney stones). Ascorbic acid may increase the risk of recurrence of calcium oxalate calculi.
Contains fish protein. Use caution with known allergies to this form of protein.
Always read the label.

References

Rice & Pea Protein References
  1. USDA National Nutrient Database for Standard Reference, Release 26. [(accessed on 18 September 2013)]; Available online: http://www.ars.usda.gov/ba/bhnrc/ndl
  2. Kalman, D. S. (2014). Amino Acid Composition of an Organic Brown Rice Protein Concentrate and Isolate Compared to Soy and Whey Concentrates and Isolates. Foods, 3(3), 394-402. http://doi.org/10.3390/foods3030394
  3. Yang, L., Chen, J.-H., Lv, J., Wu, Q., Xu, T., Zhang, H., … Yang, H.-K. (2012). Rice protein improves adiposity, body weight and reduces lipids level in rats through modification of triglyceride metabolism. Lipids in Health and Disease, 11, 24. http://doi.org/10.1186/1476-511X-11-24
  4. Li H, He H, Wang Z, Cai J, Sun B, Wu Q, Zhang Y, Zhou G, Yang L. (2016) Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats. Gene. 2016 Jul 10;585(2):256-64. doi: 10.1016/j.gene.2016.03.052. Epub 2016 Mar 31.
  5. Abou-Samra, R., Keersmaekers, L., Brienza, D., Mukherjee, R., & Macé, K. (2011). Effect of different protein sources on satiation and short-term satiety when consumed as a starter. Nutrition Journal, 10, 139. http://doi.org/10.1186/1475-2891-10-139
  6. Overduin, J., Guérin-Deremaux, L., Wils, D., & Lambers, T. T. (2015). NUTRALYS® pea protein: characterization of in vitro gastric digestion and in vivo gastrointestinal peptide responses relevant to satiety. Food & Nutrition Research, 59, 10.3402/fnr.v59.25622. http://doi.org/10.3402/fnr.v59.25622
  7. Potier, M., Darcel, N., & Tomé, D. (January 01, 2009). Protein, amino acids and the control of food intake. Current Opinion in Clinical Nutrition and Metabolic Care, 12, 1, 54-8.
  1. Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (January 01, 2014). Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study. Skin Pharmacology and Physiology, 27, 1, 47-55.
  2. Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (January 01, 2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacology and Physiology, 27, 3, 113-9.
  3. Schunck, M., Zague, V., Oesser, S., & Proksch, E. (December 01, 2015). Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Journal of Medicinal Food, 18, 12, 1340-1348.
  4. Sibilla, S., Godfrey, M., Genovese, L., Brewer, S., & Budh-Raja, A. (January 01, 2015). An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. Open Nutraceuticals Journal, 8, 1, 29-42.
  5. De Luca, C., Mikhal’chik, E. V., Suprun, M. V., Papacharalambous, M., Truhanov, A. I., & Korkina, L. G. (2016). Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxidative Medicine and Cellular Longevity, 2016, 4389410. http://doi.org/10.1155/2016/4389410
  6. Ohara H, Matsumoto H, Ito K, Iwai K, Sato K: Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources. J Agric Food Chem 2007;55:1532-1535.
  7. Iwai K, Hasegawa T, Taguchi Y, Morimatsu F, Sato K, Nakamura Y, Higashi A, Kido Y, Nakabo Y, Ohtsuki K: Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. J Agric Food Chem 2005;53:6531-6536.
  8. Mendis E, Rajapakse N, Kim SK: Antioxidant properties of a radical-scavenging peptide purified from enzymatically prepared fish skin gelatin hydrolysate. J Agric Food Chem 2005;53:581-587.
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  12. Proksch, E., Segger, D., Degwert, J., Schunck, M., Zague, V., & Oesser, S. (January 01, 2014). Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study. Skin Pharmacology and Physiology, 27, 1, 47-55.
  13. roksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (January 01, 2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacology and Physiology, 27, 3, 113-9.
  14. Schunck, M., Zague, V., Oesser, S., & Proksch, E. (December 01, 2015). Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Journal of Medicinal Food, 18, 12, 1340-1348.
  15. Sibilla, S., Godfrey, M., Genovese, L., Brewer, S., & Budh-Raja, A. (January 01, 2015). An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. Open Nutraceuticals Journal, 8, 1, 29-42.
  1. Cardile, V., Graziano, A. C. E., & Venditti, A. (January 01, 2015). Clinical evaluation of Moro (Citrus sinensis (L.) Osbeck) orange juice supplementation for the weight management. Natural Product Research, 29, 23, 2256-2260.
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  1. Gruendel, S., Otto, B., Garcia, A. L., Wagner, K., Mueller, C., Weickert, M. O., Heldwein, W., … Koebnick, C. (July 21, 2007). Carob pulp preparation rich in insoluble dietary fibre and polyphenols increases plasma glucose and serum insulin responses in combination with a glucose load in humans. British Journal of Nutrition, 98, 1, 101.
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